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Premature ovarian aging in BRCA carriers: a prototype of systemic precocious aging?

PURPOSE: Though former evidence implies a correlation of breast cancer susceptibility gene (BRCA) mutation with reduced ovarian reserve, the data is yet inconsistent. Our aim was to investigate biomarkers of ovarian aging in a cohort of young healthy carriers of the BRCA mutation. We hypothesized th...

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Detalles Bibliográficos
Autores principales: Ben-Aharon, Irit, Levi, Mattan, Margel, David, Yerushalmi, Rinat, Rizel, Shulamith, Perry, Shlomit, Sharon, Eran, Hasky, Noa, Abir, Ronit, Fisch, Benny, Tobar, Ana, Shalgi, Ruth, Stemmer, Salomon Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882308/
https://www.ncbi.nlm.nih.gov/pubmed/29662617
http://dx.doi.org/10.18632/oncotarget.24638