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Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2

Arsenic trioxide (ATO) is a traditional Chinese medicine that can induce oxidative stress for treatment of cancer cells. However, ATO may generate anti-oxidative responses to compromise the cytotoxic effect, but the underlying mechanisms remain unclear. Here we found that ATO could inhibit miR-182-5...

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Detalles Bibliográficos
Autores principales: Lin, Liang-Ting, Liu, Shin-Yi, Leu, Jyh-Der, Chang, Chun-Yuan, Chiou, Shih-Hwa, Lee, Te-Chang, Lee, Yi-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882315/
https://www.ncbi.nlm.nih.gov/pubmed/29662624
http://dx.doi.org/10.18632/oncotarget.24678