Digital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform agreement

PURPOSE: The Ki67 proliferation index is a prognostic and predictive marker in breast cancer. Manual scoring is prone to inter- and intra-observer variability. The aims of this study were to clinically validate digital image analysis (DIA) of Ki67 using virtual dual staining (VDS) on whole tissue se...

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Detalles Bibliográficos
Autores principales: Koopman, Timco, Buikema, Henk J., Hollema, Harry, de Bock, Geertruida H., van der Vegt, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882622/
https://www.ncbi.nlm.nih.gov/pubmed/29349710
http://dx.doi.org/10.1007/s10549-018-4669-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882622/
https://www.ncbi.nlm.nih.gov/pubmed/29349710
http://dx.doi.org/10.1007/s10549-018-4669-2

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