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Development of a Cell-Based Assay to Assess Binding of the proNGF Prodomain to Sortilin
Sortilin was first identified based on its activity as part of intracellular protein sorting machinery. Recently, it was discovered that sortilin also acts as a cell surface receptor for the propeptide form of nerve growth factor (proNGF), progranulin, and neurotensin. The interaction of sortilin to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882628/ https://www.ncbi.nlm.nih.gov/pubmed/29067536 http://dx.doi.org/10.1007/s10571-017-0558-1 |