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Development of a Cell-Based Assay to Assess Binding of the proNGF Prodomain to Sortilin

Sortilin was first identified based on its activity as part of intracellular protein sorting machinery. Recently, it was discovered that sortilin also acts as a cell surface receptor for the propeptide form of nerve growth factor (proNGF), progranulin, and neurotensin. The interaction of sortilin to...

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Detalles Bibliográficos
Autores principales: Malik, Ibrahim, Christensen, Søren, Stavenhagen, Jeffrey B., Dietz, Gunnar P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882628/
https://www.ncbi.nlm.nih.gov/pubmed/29067536
http://dx.doi.org/10.1007/s10571-017-0558-1