Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer

Consumption of cooked/processed meat and ethanol are lifestyle risk factors in the aetiology of breast cancer. Cooking meat generates heterocyclic amines such as 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Epidemiology, mechanistic and animal studies indicate that PhIP is a mammary carci...

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Detalles Bibliográficos
Autores principales: Malik, Durr-e-shahwar, David, Rhiannon M., Gooderham, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882637/
https://www.ncbi.nlm.nih.gov/pubmed/29362861
http://dx.doi.org/10.1007/s00204-018-2160-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882637/
https://www.ncbi.nlm.nih.gov/pubmed/29362861
http://dx.doi.org/10.1007/s00204-018-2160-9

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