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Simultaneous Monitoring of Cell-surface Receptor and Tumor-targeted Photodynamic Therapy via TdT-initiated Poly-G-Quadruplexes

Cancer cells contain a unique set of cell surface receptors that provide potential targets for tumor theranostics. Here, we propose an efficient approach to construct G-quadruplex-based aptamers that specifically recognize cell-surface receptors and monitor them in an amplified manner. This designed...

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Detalles Bibliográficos
Autores principales: Shi, Tianhui, Wang, Menglin, Li, Hao, Wang, Miao, Luo, Xingyu, Huang, Yan, Wang, Hong-Hui, Nie, Zhou, Yao, Shouzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882647/
https://www.ncbi.nlm.nih.gov/pubmed/29615769
http://dx.doi.org/10.1038/s41598-018-23902-5