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Utility of the Hebb–Williams Maze Paradigm for Translational Research in Fragile X Syndrome: A Direct Comparison of Mice and Humans

To generate meaningful information, translational research must employ paradigms that allow extrapolation from animal models to humans. However, few studies have evaluated translational paradigms on the basis of defined validation criteria. We outline three criteria for validating translational para...

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Detalles Bibliográficos
Autores principales: Boutet, Isabelle, Collin, Charles A., MacLeod, Lindsey S., Messier, Claude, Holahan, Matthew R., Berry-Kravis, Elizabeth, Gandhi, Reno M., Kogan, Cary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882825/
https://www.ncbi.nlm.nih.gov/pubmed/29643767
http://dx.doi.org/10.3389/fnmol.2018.00099