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Utility of the Hebb–Williams Maze Paradigm for Translational Research in Fragile X Syndrome: A Direct Comparison of Mice and Humans
To generate meaningful information, translational research must employ paradigms that allow extrapolation from animal models to humans. However, few studies have evaluated translational paradigms on the basis of defined validation criteria. We outline three criteria for validating translational para...
Autores principales: | Boutet, Isabelle, Collin, Charles A., MacLeod, Lindsey S., Messier, Claude, Holahan, Matthew R., Berry-Kravis, Elizabeth, Gandhi, Reno M., Kogan, Cary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882825/ https://www.ncbi.nlm.nih.gov/pubmed/29643767 http://dx.doi.org/10.3389/fnmol.2018.00099 |
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