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Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis

Cyclophilin 1 (TvCyP1), a cyclophilin type peptidyl-prolyl isomerase present in the human parasite Trichomonas vaginalis, interacts with Myb1 and assists in its nuclear translocation. Myb1 regulates the expression of ap65-1 gene that encodes for a disease causing cytoadherence enzyme. Here, we deter...

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Detalles Bibliográficos
Autores principales: Martin, Tesmine, Lou, Yuan-Chao, Chou, Chun-Chi, Wei, Shu-Yi, Sadotra, Sushant, Cho, Chao-Cheng, Lin, Meng-Hsuan, Tai, Jung-Hsiang, Hsu, Chun-Hua, Chen, Chinpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882848/
https://www.ncbi.nlm.nih.gov/pubmed/29615721
http://dx.doi.org/10.1038/s41598-018-23821-5