Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension

Background: Hypertension is characterized by sympathetic overactivity, which is associated with an enhancement in angiotensin receptor type I (AT1R) in the rostral ventrolateral medulla (RVLM). β-arrestin1, a canonical scaffold protein, has been suggested to show a negative effect on G protein-coupl...

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Detalles Bibliográficos
Autores principales: Sun, Jia-Cen, Liu, Bing, Zhang, Ru-Wen, Jiao, Pei-Lei, Tan, Xing, Wang, Yang-Kai, Wang, Wei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882868/
https://www.ncbi.nlm.nih.gov/pubmed/29643817
http://dx.doi.org/10.3389/fphys.2018.00297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882868/
https://www.ncbi.nlm.nih.gov/pubmed/29643817
http://dx.doi.org/10.3389/fphys.2018.00297

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