Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells

Apart from the relevant lipid-lowering effects, statins have demonstrated significant, although heterogeneous, anti-tumor activities in preventing breast cancer (BC) progression. To characterize the critical pathways behind the diverse responses to therapy, we investigated statin-induced changes in...

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Detalles Bibliográficos
Autores principales: Lettiero, Barbara, Inasu, Maria, Kimbung, Siker, Borgquist, Signe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882899/
https://www.ncbi.nlm.nih.gov/pubmed/29615666
http://dx.doi.org/10.1038/s41598-018-23726-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882899/
https://www.ncbi.nlm.nih.gov/pubmed/29615666
http://dx.doi.org/10.1038/s41598-018-23726-3

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