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Towards an arthritis flare-responsive drug delivery system

Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short intra-articular half-lives. Since IA severity often fluctuates over time, a local drug delivery method that titrates drug release to arthritis activity would represent an attractive paradigm in IA the...

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Detalles Bibliográficos
Autores principales: Joshi, Nitin, Yan, Jing, Levy, Seth, Bhagchandani, Sachin, Slaughter, Kai V., Sherman, Nicholas E., Amirault, Julian, Wang, Yufeng, Riegel, Logan, He, Xueyin, Rui, Tan Shi, Valic, Michael, Vemula, Praveen K., Miranda, Oscar R., Levy, Oren, Gravallese, Ellen M., Aliprantis, Antonios O., Ermann, Joerg, Karp, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882944/
https://www.ncbi.nlm.nih.gov/pubmed/29615615
http://dx.doi.org/10.1038/s41467-018-03691-1