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Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity

Pharmacological interventions to enhance fibrinolysis are effective for treating thrombotic disorders. Utilizing the in vitro U937 cell line-based fibrin degradation assay, we had previously found a cyclic pentapeptide malformin A(1) (MA(1)) as a novel activating compound for cellular fibrinolytic a...

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Detalles Bibliográficos
Autores principales: Koizumi, Yukio, Nagai, Kenichiro, Gao, Lina, Koyota, Souichi, Yamaguchi, Tomokazu, Natsui, Miyuki, Imai, Yumiko, Hasumi, Keiji, Sugiyama, Toshihiro, Kuba, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882963/
https://www.ncbi.nlm.nih.gov/pubmed/29615689
http://dx.doi.org/10.1038/s41598-018-23745-0