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Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity
Pharmacological interventions to enhance fibrinolysis are effective for treating thrombotic disorders. Utilizing the in vitro U937 cell line-based fibrin degradation assay, we had previously found a cyclic pentapeptide malformin A(1) (MA(1)) as a novel activating compound for cellular fibrinolytic a...
Autores principales: | Koizumi, Yukio, Nagai, Kenichiro, Gao, Lina, Koyota, Souichi, Yamaguchi, Tomokazu, Natsui, Miyuki, Imai, Yumiko, Hasumi, Keiji, Sugiyama, Toshihiro, Kuba, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882963/ https://www.ncbi.nlm.nih.gov/pubmed/29615689 http://dx.doi.org/10.1038/s41598-018-23745-0 |
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