Aspermerodione, a novel fungal metabolite with an unusual 2,6-dioxabicyclo[2.2.1]heptane skeleton, as an inhibitor of penicillin-binding protein 2a

Rising drug resistance limits the treatment options infected by methicillin-resistant Staphylococcus aureus (MRSA). A promising solution for overcoming the resistance of MRSA is to inhibit the penicillin-binding protein 2a (PBP2a). A novel terpene-polyketide hybrid meroterpenoid, aspermerodione (1),...

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Detalles Bibliográficos
Autores principales: Qiao, Yuben, Zhang, Xiaotian, He, Yan, Sun, Weiguang, Feng, Wenya, Liu, Junjun, Hu, Zhengxi, Xu, Qianqian, Zhu, Hucheng, Zhang, Jinwen, Luo, Zengwei, Wang, Jianping, Xue, Yongbo, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882964/
https://www.ncbi.nlm.nih.gov/pubmed/29615766
http://dx.doi.org/10.1038/s41598-018-23817-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882964/
https://www.ncbi.nlm.nih.gov/pubmed/29615766
http://dx.doi.org/10.1038/s41598-018-23817-1

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