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Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells

Effective transfection of genetic molecules such as DNA usually relies on vectors that can reversibly uptake and release these molecules, and protect them from digestion by nuclease. Non-viral vectors meeting these requirements are rare due to the lack of specific interactions with DNA. Here, we des...

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Detalles Bibliográficos
Autores principales: Peng, Shuang, Bie, Binglin, Sun, Yangzesheng, Liu, Min, Cong, Hengjiang, Zhou, Wentao, Xia, Yucong, Tang, Heng, Deng, Hexiang, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882967/
https://www.ncbi.nlm.nih.gov/pubmed/29615605
http://dx.doi.org/10.1038/s41467-018-03650-w