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Lentiviral vector delivery of short hairpin RNA to NgR1 promotes nerve regeneration and locomotor recovery in injured rat spinal cord
Nogo receptor 1 (NgR1) is a high-affinity receptor of myelin-associated inhibitors (MAIs), and suppresses neurogenesis. Lentiviral vector are commonly used to alter the expression of targeted genes. However, little is known about the potential function of lentiviral vector harboring NgR1 shRNA (LV-N...
Autores principales: | Zhao, Xiaoyang, Peng, Zhiming, Long, Lingli, Chen, Ningning, Zheng, Haichong, Deng, David Y. B., Wan, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882972/ https://www.ncbi.nlm.nih.gov/pubmed/29615686 http://dx.doi.org/10.1038/s41598-018-23751-2 |
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