Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux

Many organisms have several similar transporters with different affinities for the same substrate. Typically, high-affinity transporters are expressed when substrate is scarce and low-affinity ones when it is abundant. The benefit of using low instead of high-affinity transporters remains unclear, e...

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Detalles Bibliográficos
Autores principales: Bosdriesz, Evert, Wortel, Meike T., Haanstra, Jurgen R., Wagner, Marijke J., de la Torre Cortés, Pilar, Teusink, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883050/
https://www.ncbi.nlm.nih.gov/pubmed/29615663
http://dx.doi.org/10.1038/s41598-018-23528-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883050/
https://www.ncbi.nlm.nih.gov/pubmed/29615663
http://dx.doi.org/10.1038/s41598-018-23528-7

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