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Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
Many organisms have several similar transporters with different affinities for the same substrate. Typically, high-affinity transporters are expressed when substrate is scarce and low-affinity ones when it is abundant. The benefit of using low instead of high-affinity transporters remains unclear, e...
Autores principales: | Bosdriesz, Evert, Wortel, Meike T., Haanstra, Jurgen R., Wagner, Marijke J., de la Torre Cortés, Pilar, Teusink, Bas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883050/ https://www.ncbi.nlm.nih.gov/pubmed/29615663 http://dx.doi.org/10.1038/s41598-018-23528-7 |
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