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A novel trivalent HPV 16/18/58 vaccine with anti-HPV 16 and 18 neutralizing antibody responses comparable to those induced by the Gardasil quadrivalent vaccine in rhesus macaque model

Persistent infection with human papillomavirus (HPV) is a key factor in the development of precancerous lesions and invasive cervical cancer. Prophylactic vaccines to immunize against HPV are an effective approach to reducing HPV related disease burden. In this study, we investigated the immunogenic...

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Detalles Bibliográficos
Autores principales: Yin, Fei, Wang, Yajun, Chen, Na, Jiang, Dunquan, Qiu, Yefeng, Wang, Yan, Yan, Mei, Chen, Jianping, Zhang, Haijiang, Liu, Yongjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883244/
https://www.ncbi.nlm.nih.gov/pubmed/28720462
http://dx.doi.org/10.1016/j.pvr.2017.02.005