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A novel trivalent HPV 16/18/58 vaccine with anti-HPV 16 and 18 neutralizing antibody responses comparable to those induced by the Gardasil quadrivalent vaccine in rhesus macaque model
Persistent infection with human papillomavirus (HPV) is a key factor in the development of precancerous lesions and invasive cervical cancer. Prophylactic vaccines to immunize against HPV are an effective approach to reducing HPV related disease burden. In this study, we investigated the immunogenic...
Autores principales: | Yin, Fei, Wang, Yajun, Chen, Na, Jiang, Dunquan, Qiu, Yefeng, Wang, Yan, Yan, Mei, Chen, Jianping, Zhang, Haijiang, Liu, Yongjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883244/ https://www.ncbi.nlm.nih.gov/pubmed/28720462 http://dx.doi.org/10.1016/j.pvr.2017.02.005 |
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