Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration

BACKGROUND: Aging is the strongest risk factor for neurodegenerative diseases and extended age results in neuronal degeneration and functional decline in the visual system. Among many contributing factors to age-related deterioration of neurons is an insufficient activation of the Unfolded Protein R...

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Detalles Bibliográficos
Autores principales: McLaughlin, Todd, Falkowski, Marek, Park, Jae Whan, Keegan, Stephen, Elliott, Michael, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883257/
https://www.ncbi.nlm.nih.gov/pubmed/29615095
http://dx.doi.org/10.1186/s13024-018-0250-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883257/
https://www.ncbi.nlm.nih.gov/pubmed/29615095
http://dx.doi.org/10.1186/s13024-018-0250-z

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