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Transient reduction of DNA methylation at the onset of meiosis in male mice

BACKGROUND: Meiosis is a specialized germ cell cycle that generates haploid gametes. In the initial stage of meiosis, meiotic prophase I (MPI), homologous chromosomes pair and recombine. Extensive changes in chromatin in MPI raise an important question concerning the contribution of epigenetic mecha...

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Detalles Bibliográficos
Autores principales: Gaysinskaya, Valeriya, Miller, Brendan F., De Luca, Chiara, van der Heijden, Godfried W., Hansen, Kasper D., Bortvin, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883305/
https://www.ncbi.nlm.nih.gov/pubmed/29618374
http://dx.doi.org/10.1186/s13072-018-0186-0