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Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes
Insect nephrocytes provide a valuable model for kidney disease, as they are structurally and functionally homologous to mammalian kidney podocytes. They possess an exceptional macromolecular assembly, the nephrocyte diaphragm (ND), which serves as a filtration barrier and helps maintain tissue homeo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883325/ https://www.ncbi.nlm.nih.gov/pubmed/29458174 http://dx.doi.org/10.1016/j.yexcr.2018.02.015 |