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Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes

Insect nephrocytes provide a valuable model for kidney disease, as they are structurally and functionally homologous to mammalian kidney podocytes. They possess an exceptional macromolecular assembly, the nephrocyte diaphragm (ND), which serves as a filtration barrier and helps maintain tissue homeo...

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Detalles Bibliográficos
Autores principales: Muraleedharan, Simi, Sam, Aksah, Skaer, Helen, Inamdar, Maneesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883325/
https://www.ncbi.nlm.nih.gov/pubmed/29458174
http://dx.doi.org/10.1016/j.yexcr.2018.02.015