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Calcium Signaling, PKC Gamma, IP(3)R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development

BACKGROUND: Spinocerebellar ataxias (SCAs) are a group of cerebellar diseases characterized by progressive ataxia and cerebellar atrophy. Several forms of SCAs are caused by missense mutations or deletions in genes related to calcium signaling in Purkinje cells. Among them, spinocerebellar ataxia ty...

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Detalles Bibliográficos
Autores principales: Shimobayashi, Etsuko, Kapfhammer, Josef P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883377/
https://www.ncbi.nlm.nih.gov/pubmed/28554312
http://dx.doi.org/10.2174/1570159X15666170529104000