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Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic?

INTRODUCTION: Pragmatic randomized controlled trials (RCTs) mimic usual clinical practice and they are critical to inform decision-making by patients, clinicians and policy-makers in real-world settings. Pragmatic RCTs assess effectiveness of available medicines, while explanatory RCTs assess effica...

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Detalles Bibliográficos
Autores principales: Dal-Ré, Rafael, Janiaud, Perrine, Ioannidis, John P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883397/
https://www.ncbi.nlm.nih.gov/pubmed/29615035
http://dx.doi.org/10.1186/s12916-018-1038-2