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Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic?
INTRODUCTION: Pragmatic randomized controlled trials (RCTs) mimic usual clinical practice and they are critical to inform decision-making by patients, clinicians and policy-makers in real-world settings. Pragmatic RCTs assess effectiveness of available medicines, while explanatory RCTs assess effica...
Autores principales: | Dal-Ré, Rafael, Janiaud, Perrine, Ioannidis, John P. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883397/ https://www.ncbi.nlm.nih.gov/pubmed/29615035 http://dx.doi.org/10.1186/s12916-018-1038-2 |
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