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Combined life-threatening thromboses and hemorrhages in a patient with afibrinogenemia and antithrombin deficiency

BACKGROUND: Patients with congenital afibrinogenemia suffer from spontaneous recurrent severe bleeding. While fibrinogen concentrates are known to effectively treat bleeding episodes, thrombotic complications often occur upon replacement therapy, rendering clinical management highly challenging. CAS...

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Detalles Bibliográficos
Autores principales: Le Quellec, S., Desjonqueres, A., Rugeri, L., Desmurs Clavel, H., Farhat, F., Mechtouff, L., Dargaud, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883424/
https://www.ncbi.nlm.nih.gov/pubmed/29636644
http://dx.doi.org/10.1186/s12959-018-0162-8