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Combined life-threatening thromboses and hemorrhages in a patient with afibrinogenemia and antithrombin deficiency
BACKGROUND: Patients with congenital afibrinogenemia suffer from spontaneous recurrent severe bleeding. While fibrinogen concentrates are known to effectively treat bleeding episodes, thrombotic complications often occur upon replacement therapy, rendering clinical management highly challenging. CAS...
Autores principales: | Le Quellec, S., Desjonqueres, A., Rugeri, L., Desmurs Clavel, H., Farhat, F., Mechtouff, L., Dargaud, Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883424/ https://www.ncbi.nlm.nih.gov/pubmed/29636644 http://dx.doi.org/10.1186/s12959-018-0162-8 |
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