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Role of cytarabine in paediatric acute promyelocytic leukemia treated with the combination of all-trans retinoic acid and arsenic trioxide: a randomized controlled trial

BACKGROUND: The combination of all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) has been suggested to be safe and effective for adult acute promyelocytic leukaemia (APL). As of 2010, the role of cytarabine (Ara-C) in APL was controversial. The aim of this study was to test the efficacy and...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Zou, Yao, Chen, Yumei, Guo, Ye, Yang, Wenyu, Chen, Xiaojuan, Wang, Shuchun, Liu, Xiaoming, Ruan, Min, Zhang, Jiayuan, Liu, Tianfeng, Liu, Fang, Qi, Benquan, An, Wenbin, Ren, Yuanyuan, Chang, Lixian, Zhu, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883545/
https://www.ncbi.nlm.nih.gov/pubmed/29615003
http://dx.doi.org/10.1186/s12885-018-4280-2