Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors

BACKGROUND: The expression of a specific combination of transcription factors (TFs) in the multipotent progenitor cells (MPCs) is critical for determining pancreatic cell fate. NKX6.1 expression in PDX1(+) MPCs is required for functional β cell generation. We have recently demonstrated the generatio...

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Detalles Bibliográficos
Autores principales: Aigha, Idil I., Memon, Bushra, Elsayed, Ahmed K., Abdelalim, Essam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883581/
https://www.ncbi.nlm.nih.gov/pubmed/29615106
http://dx.doi.org/10.1186/s13287-018-0834-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883581/
https://www.ncbi.nlm.nih.gov/pubmed/29615106
http://dx.doi.org/10.1186/s13287-018-0834-0

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