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Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities

The biological underpinnings for racial disparities in colorectal cancer (CRC) incidence remain to be elucidated. We have previously reported that the cohesin SA-1 down-regulation is an early event in colon carcinogenesis which is dramatically accentuated in African-Americans. In order to investigat...

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Detalles Bibliográficos
Autores principales: Datta, Somenath, Sherva, Richard M., De La Cruz, Mart, Long, Michelle T., Roy, Priya, Backman, Vadim, Chowdhury, Sanjib, Roy, Hemant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883624/
https://www.ncbi.nlm.nih.gov/pubmed/29471289
http://dx.doi.org/10.1016/j.neo.2018.01.003