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Basal p53 expression is indispensable for mesenchymal stem cell integrity

Marrow-resident mesenchymal stem cells (MSCs) serve as a functional component of the perivascular niche that regulates hematopoiesis. They also represent the main source of bone formed in adult bone marrow, and their bifurcation to osteoblast and adipocyte lineages plays a key role in skeletal homeo...

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Detalles Bibliográficos
Autores principales: Boregowda, Siddaraju V., Krishnappa, Veena, Strivelli, Jacqueline, Haga, Christopher L., Booker, Cori N., Phinney, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883824/
https://www.ncbi.nlm.nih.gov/pubmed/29311623
http://dx.doi.org/10.1038/s41418-017-0004-4