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Clonal analysis of lineage fate in native hematopoiesis

Hematopoiesis, the process of mature blood and immune cell production, is functionally organized as a hierarchy, with self-renewing hematopoietic stem cells (HSCs) and multipotent progenitor (MPP) cells sitting at the very top(1,2). Multiple models have been proposed as to what the earliest lineage...

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Detalles Bibliográficos
Autores principales: Rodriguez-Fraticelli, Alejo E., Wolock, Samuel L., Weinreb, Caleb S., Panero, Riccardo, Patel, Sachin H., Jankovic, Maja, Sun, Jianlong, Calogero, Raffaele A., Klein, Allon M., Camargo, Fernando D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884107/
https://www.ncbi.nlm.nih.gov/pubmed/29323290
http://dx.doi.org/10.1038/nature25168