The Proliferative Response to p27 Down-Regulation in Estrogen Plus Progestin Hormonal Therapy is Lost in Breast Tumors

Increased proliferation and breast cancer risk has been observed in postmenopausal women receiving estrogen (E) + progestin hormone replacement therapy (HRT). Progestin action is mediated through two progesterone receptor (PR) isoforms, PRA and PRB, with unique transcriptional activity and function....

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Detalles Bibliográficos
Autores principales: Aupperlee, Mark D., Kariagina, Anastasia, Zaremba, Nicole, Basson, Marc D., Schwartz, Richard C., Haslam, Sandra Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884216/
https://www.ncbi.nlm.nih.gov/pubmed/29524829
http://dx.doi.org/10.1016/j.tranon.2018.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884216/
https://www.ncbi.nlm.nih.gov/pubmed/29524829
http://dx.doi.org/10.1016/j.tranon.2018.02.011

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