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DAB2IP Downregulation Enhances the Proliferation and Metastasis of Human Gastric Cancer Cells by Derepressing the ERK1/2 Pathway

DAB2IP (DOC2/DAB2 interactive protein) is downregulated in several cancer types, and its downregulation is involved in tumor cell proliferation, apoptosis, metastasis, and epithelial-mesenchymal transition (EMT). We aimed to investigate the potential role of DAB2IP in the development and progression...

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Detalles Bibliográficos
Autores principales: Sun, Liang, Yao, Yizhou, Lu, Ting, Shang, Zengfu, Zhan, Shenghua, Shi, Weiqiang, Pan, Guofeng, Zhu, Xinguo, He, Songbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884246/
https://www.ncbi.nlm.nih.gov/pubmed/29743885
http://dx.doi.org/10.1155/2018/2968252