Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses

Recently, we identified a unique -2/-1 ribosomal frameshift mechanism in PRRSV, which yields two truncated forms of nonstructural protein (nsp) 2 variants, nsp2TF and nsp2N. Here, in vitro expression of individual PRRSV nsp2TF and nsp2N demonstrated their ability to suppress cellular innate immune r...

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Detalles Bibliográficos
Autores principales: Li, Y., Shang, P., Shyu, D., Carrillo, C., Naraghi-Arani, P., Jaing, Crystal J., Renukaradhya, G.J., Firth, A.E., Snijder, E.J., Fang, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884420/
https://www.ncbi.nlm.nih.gov/pubmed/29325778
http://dx.doi.org/10.1016/j.virol.2017.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884420/
https://www.ncbi.nlm.nih.gov/pubmed/29325778
http://dx.doi.org/10.1016/j.virol.2017.12.017

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