PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules

Inhibition of the phospholipid phosphatase and tumor suppressor PTEN leads to excessive polarized cell growth during directed cell migration and neurite outgrowth. These processes require the precise regulation of both the actin and microtubule cytoskeleton. While PTEN is known to regulate actin dyn...

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Detalles Bibliográficos
Autores principales: Kath, Christina, Goni-Oliver, Paloma, Müller, Rainer, Schultz, Carsten, Haucke, Volker, Eickholt, Britta, Schmoranzer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884485/
https://www.ncbi.nlm.nih.gov/pubmed/29617365
http://dx.doi.org/10.1371/journal.pone.0193257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884485/
https://www.ncbi.nlm.nih.gov/pubmed/29617365
http://dx.doi.org/10.1371/journal.pone.0193257

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