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PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
Inhibition of the phospholipid phosphatase and tumor suppressor PTEN leads to excessive polarized cell growth during directed cell migration and neurite outgrowth. These processes require the precise regulation of both the actin and microtubule cytoskeleton. While PTEN is known to regulate actin dyn...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884485/ https://www.ncbi.nlm.nih.gov/pubmed/29617365 http://dx.doi.org/10.1371/journal.pone.0193257 |