Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy

Prostasin (CAP1/PRSS8) is a glycosylphosphatidylinositol (GPI)-anchored serine protease that is essential for epithelial development and overall survival in mice. Prostasin is regulated primarily by the transmembrane serine protease inhibitor, hepatocyte growth factor activator inhibitor (HAI)-2, an...

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Detalles Bibliográficos
Autores principales: Szabo, Roman, Bugge, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884512/
https://www.ncbi.nlm.nih.gov/pubmed/29617460
http://dx.doi.org/10.1371/journal.pone.0194660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884512/
https://www.ncbi.nlm.nih.gov/pubmed/29617460
http://dx.doi.org/10.1371/journal.pone.0194660

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