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The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

The still largely obscure molecular events in the glioblastoma oncogenesis, a primary brain tumor characterized by an inevitably dismal prognosis, impel for investigation. The importance of Long noncoding RNAs as regulators of gene expression has recently become evident. Among them, H19 has a recogn...

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Detalles Bibliográficos
Autores principales: Fazi, Barbara, Garbo, Sabrina, Toschi, Nicola, Mangiola, Annunziato, Lombari, Malinska, Sicari, Daria, Battistelli, Cecilia, Galardi, Silvia, Michienzi, Alessandro, Trevisi, Gianluca, Harari-Steinfeld, Rona, Cicchini, Carla, Ciafrè, Silvia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884644/
https://www.ncbi.nlm.nih.gov/pubmed/29643989
http://dx.doi.org/10.18632/oncotarget.24496