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Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity

MiR-106b is an oncomir and a potential target for anti-cancer therapy. We hypothesize that grape seed procyanidin extract (GSE) exerts antineoplastic effects on lung cancer through modulations of miR-106b and its downstream target. We found that GSE significantly down-regulated miR-106b in a variety...

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Detalles Bibliográficos
Autores principales: Xue, Bingye, Lu, Qing-Yi, Massie, Larry, Qualls, Clifford, Mao, Jenny T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884649/
https://www.ncbi.nlm.nih.gov/pubmed/29643994
http://dx.doi.org/10.18632/oncotarget.24528