New antimicrobial peptide kills drug-resistant pathogens without detectable resistance

Clavaspirin peptide (CSP) is derived from the pharyngeal tissues of the tunicate Styela clava. The 23-amino acid peptide is histidine-rich and amidated at the N-terminus. CSP possesses low antimicrobial and high hemolytic activity at pH 7.4. Therefore, we designed 4 CSP analogs with substituted hydr...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Kook, Luchian, Tudor, Park, Yoonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884652/
https://www.ncbi.nlm.nih.gov/pubmed/29643997
http://dx.doi.org/10.18632/oncotarget.24582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884652/
https://www.ncbi.nlm.nih.gov/pubmed/29643997
http://dx.doi.org/10.18632/oncotarget.24582

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