CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

High grade serous ovarian cancer (HGSOC) is a disease with a high relapse rate and poor overall survival despite good initial responses to platinum-based therapy. Cell cycle inhibition with targeted CDK4/6 inhibitors is a new therapeutic approach showing promise as a maintenance therapy in cancer. A...

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Detalles Bibliográficos
Autores principales: Iyengar, Mangala, O’Hayer, Patrick, Cole, Alex, Sebastian, Tara, Yang, Kun, Coffman, Lan, Buckanovich, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884655/
https://www.ncbi.nlm.nih.gov/pubmed/29644000
http://dx.doi.org/10.18632/oncotarget.24585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884655/
https://www.ncbi.nlm.nih.gov/pubmed/29644000
http://dx.doi.org/10.18632/oncotarget.24585

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