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CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

High grade serous ovarian cancer (HGSOC) is a disease with a high relapse rate and poor overall survival despite good initial responses to platinum-based therapy. Cell cycle inhibition with targeted CDK4/6 inhibitors is a new therapeutic approach showing promise as a maintenance therapy in cancer. A...

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Detalles Bibliográficos
Autores principales:	Iyengar, Mangala, O’Hayer, Patrick, Cole, Alex, Sebastian, Tara, Yang, Kun, Coffman, Lan, Buckanovich, Ronald J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884655/ https://www.ncbi.nlm.nih.gov/pubmed/29644000 http://dx.doi.org/10.18632/oncotarget.24585

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