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Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency

The growth of cancer metastases in the liver depends on a permissive interaction with the hepatic microenvironment and neutrophils can contribute to this interaction, either positively or negatively, depending on their phenotype. Here we investigated the role of IGF-I in the control of the tumor mic...

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Detalles Bibliográficos
Autores principales: Rayes, Roni F., Milette, Simon, Fernandez, Maria Celia, Ham, Boram, Wang, Ni, Bourdeau, France, Perrino, Stephanie, Yakar, Shoshana, Brodt, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884657/
https://www.ncbi.nlm.nih.gov/pubmed/29644002
http://dx.doi.org/10.18632/oncotarget.24593