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Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency
The growth of cancer metastases in the liver depends on a permissive interaction with the hepatic microenvironment and neutrophils can contribute to this interaction, either positively or negatively, depending on their phenotype. Here we investigated the role of IGF-I in the control of the tumor mic...
Autores principales: | Rayes, Roni F., Milette, Simon, Fernandez, Maria Celia, Ham, Boram, Wang, Ni, Bourdeau, France, Perrino, Stephanie, Yakar, Shoshana, Brodt, Pnina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884657/ https://www.ncbi.nlm.nih.gov/pubmed/29644002 http://dx.doi.org/10.18632/oncotarget.24593 |
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