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IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma

Glioblastoma (GBM) is a highly aggressive brain tumor characterized by a high rate of vascularization. However, therapeutic targeting of the vasculature through anti-vascular endothelial growth factor (VEGF) treatment has been disappointing, for which Angiopoietin-2 (Ang-2) upregulation has partly b...

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Detalles Bibliográficos
Autores principales: Conroy, Siobhan, Kruyt, Frank A.E., Wagemakers, Michiel, Bhat, Krishna P.L., den Dunnen, Wilfred F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884659/
https://www.ncbi.nlm.nih.gov/pubmed/29644004
http://dx.doi.org/10.18632/oncotarget.24595