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Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling

Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cell state. Previously, we uncovered processes in the Saccharomyces cerevisiae pheromone response system (PRS) that reduced cell‐to‐cell variability in signal strength and cellular respons...

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Detalles Bibliográficos
Autores principales: Pesce, C Gustavo, Zdraljevic, Stefan, Peria, William J, Bush, Alan, Repetto, María Victoria, Rockwell, Daniel, Yu, Richard C, Colman‐Lerner, Alejandro, Brent, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884679/
https://www.ncbi.nlm.nih.gov/pubmed/29618636
http://dx.doi.org/10.15252/msb.20167390