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Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury

Painful intervertebral disc degeneration is mediated by inflammation that modulates glycosylation and induces hyperinnervation and sensory sensitization, which result in discogenic pain. Hyaluronic acid (HA) used as a therapeutic biomaterial can reduce inflammation and pain, but the effects of HA th...

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Detalles Bibliográficos
Autores principales: Mohd Isa, Isma Liza, Abbah, Sunny A., Kilcoyne, Michelle, Sakai, Daisuke, Dockery, Peter, Finn, David P., Pandit, Abhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884685/
https://www.ncbi.nlm.nih.gov/pubmed/29632893
http://dx.doi.org/10.1126/sciadv.aaq0597